院長

島田 健永

2020年5月にオープンいたしました、しまだ循環器・糖尿病内科クリニックでは、当院で必要な検査を完結させて、エビデンス（科学的根拠）をもって診断・治療にあたらせていただきます。

当院が注力して診させていただいております循環器疾患では、“きめ細やかな診療”がとても大事で、特に今後ご高齢の方の間で増えると考えられる心不全の管理は、大病院にありがちな1～2ヶ月に1回という通院では難しく、1～2週間に1回の通院といったようなきめ細やかな診療が必要になります。
こうしたことを考えた場合、患者様のお住まいの地域で専門知識と経験を持った専門医が診療にあたるべきと思い、このクリニックをオープンした次第です。

当院がございます大阪市旭区千林大宮は、昔ながらのいい雰囲気が残る町で、お住まいになられている方も皆様、気さくで飾らない方ばかりです。
そうした地域にお住まいの方々に、大病院での通院では難しい、期間的にも中身的にもきめ細やかな診療をお届けすることで、毎日の健康を見守らせていただきます。

略歴

資格

日本循環器学会 循環器専門医

院長のユニークな研究

赤ワイン好きが講じて、サントリーさんと共同研究を行ってきました。
赤ワインが心臓の血流を増加させる作用を持つことを世界で初めて証明しました。世界的に有名な医学雑誌LANCETに論文が取り上げられ、朝日新聞一面にも掲載されました。白ワインやウオッカにはなく、赤ワインに含まれるポリフェノールが血管に作用した結果と考えられています。

業績　和文論文

1. 赤ワインと冠循環予備能.

島田健永, 吉川純一： 呼吸と循環, 49巻12号:1207-1212,2001.

2. 冠動脈血流予備能からみた赤ワインの効用.

島田健永, 吉川純一： 心エコー, 2巻8号: 666-671, 2001.

3. 急性冠症候群における血漿Adiponectin濃度の意義.

中村泰浩, 島田健永, 福田大受, 江原省一, 葭山稔, 竹内一秀, 吉川純一： 血栓と循環, 10巻3号 : 406, 2002.

4. 冠動脈ステント留置後,慢性期におけるシロスタゾール投与群とチクロピジン投与群の比較検討　血管内超音波法を用いた検討.

坂本常守, 島田健永, 楠山貴教, 福田大受, 西岡弘樹, 江原省一, 田中篤, 葭山稔,
竹内一秀, 吉川純一： 血栓と循環, 11巻4号: 378, 2003.

5. 冠動脈プラークに対するHMG-CoA還元酵素阻害剤(スタチン)の退縮作用について 血管内超音波(IVUS)によるvolume metric解析. 西岡弘樹, 清水成人, 藤井隆生, 西矢大輔, 吉村隆喜, 広瀬真,
片岡亨, 坂本常守, 紙森公雄, 島田健永, 吉川純一： 血栓と循環, 11巻4号: 384-385, 2003.

6. 肥満症・メタボリックシンドローム　最新診療コンセンサス メタボリックシンドローム治療の将来展望　食生活改善によるメタボリックシンドローム治療.

島田健永, 吉川純一： 医学のあゆみ, 213巻6号: 651-656,2005.

7. 高コレステロール血症患者の冠血流予備能におけるフルバスタチン治療の効果.

藤本浩平, 穂積健之, 渡辺弘之, 島田健永, 竹内正明, 坂上祐司, 清水成人, 大塚亮, 河瀬吉雄, 坂元一夫, 葭山稔, 馬場雄治,
土師一夫, 吉川純一： 血管, 28巻1号: 25, 2005.

8. マルチモダリティによるCardiac Imaging 2006　臨床編　早期診断・治療をめざす新しい戦略 USによる戦略とその実際　心エコー図検査における虚血性心疾患の診断.

田中秀昌, 島田健永：INNERVISION, 21巻5号: 51-53, 2006.

9. 急性冠症候群患者にみられた左冠動脈回旋枝のマルチプルプラークラプチャーの1例.

實正哲, 田中秀昌, 吉田健, 島田健永, 吉川純一： THE CIRCULATION FRONTIER, 10巻1号: 60-63,2006.

10. ACS(急性冠症候群)　病態理解・治療の新しい展開 MMP-9とCoronary Plaque Rupture.

実正哲, 福田大受, 島田健永, 田中秀昌, 吉田健, 吉川純一：診療と新薬, 43巻3号:268-269, 2006.

11. 急性冠症候群診療　そこが知りたいbest strategy 診る　不安定粥腫を診る　CTによるアプローチ.

島田健永： Heart View, 11巻9号: 986-994, 2007.

12. 冠動脈疾患の診断　Update 冠動脈CTにてプラークラプチャーを観察する.

賀来大輔, 島田健永, 田中秀昌, 實正哲, 吉田健, 吉川純一： 診療と新薬, 44巻11号: 1255-1256, 2007.

13. 不安障害　精神科、一般医どっちがみる　循環器の立場から.

島田健永： 大阪府内科医会会誌, 17巻1号: 26-30, 2008.

14. 心血管マルチバイオマーカー・ストラテジー 新規バイオマーカーの臨床展開　心血管リモデリングとMMP.

島田健永, 吉川純一： 医学のあゆみ, 224巻5号：403-407, 2008.

15. 肺血栓塞栓症 64-slice MDCTによる肺動脈・下肢静脈同時撮影法　肺血栓塞栓症の診断において.

田中秀昌, 島田健永, 實正哲, 吉田健, 吉川純一： 診療と新薬, 45巻4号: 349-351, 2008.

16. 運動負荷による左房機能変化について　RT3Dエコーでの研究.

藤本宏美, 川崎俊博, 福田祥大, 砂田寛恵, 前田久美子, 田中秀昌, 實正哲, 吉田健, 島田健永, 吉川純一, 葭山稔： 超音波検査技術,
33巻2号: 165, 2008.

17. 心疾患とCKD(慢性腎臓病) 新しい動脈硬化指標としての頸動脈ストレイン　CKDとの関連.

福田祥大, 島田健永, 川崎俊博, 河野靖, 前田久美子, 實正哲, 田口晴之, 葭山稔, 吉川純一： 診療と新薬,
46巻12号: 1246-1247, 2009.

18. 血栓と循環の検査法　血管内皮機能シリーズ　冠動脈における血管内皮機能測定.

島田健永： 血栓と循環, 17巻2号: 220-225, 2009.

19. 胸部症状を呈する患者の診断・治療に関する実態調査.

島田健永：診断と治療, 97巻2号: 391-395, 2009.

20. 大規模臨床試験から何を学ぶか 心血管イベント抑制のための高血圧治療　高血圧の裏に潜む耐糖能障害.

野原隆司, 藤井繁樹, 武俊介, 高見武志, 島田健永： 血圧, 16巻9号: 81-87, 2009.

21. 自由壁破裂を救命しえた陳旧性前壁中隔梗塞の一例.

宮花礼子, 川崎俊博, 福田祥大, 前田久美子, 藤本宏美, 豊島範子, 河野靖, 實正哲, 田口晴之, 島田健永, 葭山稔, 吉川純一： 超音波検査技術,34巻6号: 711, 2009.

22. 夜間勤務による血管内皮機能障害におけるアロマセラピーの有用性.

藤本宏美, 川崎俊博, 福田祥大, 前田久美子, 宮花礼子, 實正哲, 田口晴之, 島田健永, 葭山稔, 吉川純一： 超音波検査技術, 34巻6号:
712, 2009.

23. 心疾患とCKD(慢性腎臓病) 新しい動脈硬化指標としての頸動脈ストレイン　CKDとの関連.

福田祥大, 島田健永, 川崎俊博, 河野靖, 前田久美子, 實正哲, 田口晴之, 葭山稔, 吉川純一： 診療と新薬,
46巻12号: 1246-1247, 2009.

24. 虚血性心疾患の治療戦略における硝酸薬の役割 冠動脈CT時代における硝酸薬の役割.

島田健永： Therapeutic Research, 31巻1号: 39-45, 2010.

25. MDCTをどう臨床に活用するか 識る　MDCTによる大動脈弁狭窄と冠動脈病変の同時診断.

田中秀昌, 島田健永： Heart View, 14巻7号: 794-799, 2010.

26. 心不全における弁膜疾患 僧帽弁尖に対する左室内血流の時間的・空間的広がり.

福田祥大, 島田健永, 宮花礼子, 川崎俊博, 河野靖, 前田久美子, 實正哲, 田口晴之, 葭山稔, 塩田隆弘, 吉川純一： 診療と新薬,
47巻6号: 586-587, 2010.

27. 機械まかせにしない心臓CTの実力をつける 冠動脈石灰化に対する心筋からのアプローチ.

吉田健, 島田健永： 心臓血管画像MOOK, 3巻: 117-121, 2010.

28. 糖尿病と循環器疾患 糖尿病と血管不全.

島田健永: Cardiovascular frontier, 2巻2号:14-20, 2011.

29. 抗血小板療法は誰にどこまで必要か　ATIS予防.

島田健永： Coronary Intervention, 7巻5号: XXII-XXIII, 2011.

30. 新しい人材養成への道 オフザジョブトレーニングの現状　医療手技教育とシステム構築　大阪市立大学医学部附属病院スキルスシミュレーションセンターの取組みを中心に.

首藤太一, 奥幸子, 岡田明子, 小林正宜, 巳波真希,
津村えりか, 海野貴史, 衣畑成紀, 岡崎博敏, 島田健永, 森村美奈, 津村圭, 新藤光郎, 溝端 康光, 廣橋一裕： 救急医学, 35巻12号: 1688-1694, 2011.

31. わかりやすい血管疾患と薬物療法(第8回)　動脈硬化とARB.

島田健永： Vascular Lab, 9巻2号: 186-189, 2012.

32. PCI患者におけるATIS予防の重要性　抗血小板療法は誰にどこまで必要か　ATIS予防.

島田健永： Coronary Intervention, 8巻2号: XXVIII-XXIX, 2012.

33. PCI患者のATISマネジメントUp to date　PCI患者の全身血管管理. 水野清雄, 島田健永, 坪川明義, 三澤克史, 藤野晋, 中野顯, 荒川健一郎, 竹森一司： Pharma Medica,
30巻8号: 81-87, 2012.

34. DES留置後の抗血小板薬の使い方 脳・心血管イベント発症抑制における長期的抗血小板療法の意義.

島田健永： Coronary Intervention, 9巻1号: 70-74, 2013.

35. 冠動脈CT血管造影法におけるnapkin-ring signの病態と急性冠症候群発症の危険性.

大塚 憲一郎, 島田 健永.日本医事新報 (0385-9215)4688号 60-61.2014.

36. ワイヤレス12誘導心電計を用いた運動負荷心エコー図検査の有用性.

宮花 礼子, 川崎 俊博, 前田 久美子, 上原 久美子, 兵頭 永一, 田口 晴之, 島田 健永, 吉川 純一. 医学検査
63巻2号,140-145.2014.

37. 血管内皮機能改善のための最新治療 新しい心臓リハビリテーション　全身加速ベッドと四肢駆血を冠血流予備能(CFR)から評価する.

福田 祥大, 島田 健永.脈管学 54巻5号, 67-71,2014.

38. 急性心筋梗塞発症予防に何が必要か.

島田 健永. 大阪府内科医会会誌 23巻2号181-185.2014.

業績　英語業績

1. Usefulness of pre- and post-stent optical frequency domain imaging findings in the prediction of
periprocedural cardiac troponin elevation in patients with coronary artery disease. Heart Vessels. 2019 Sep 27.

2. Ankle-brachial index, arterial stiffness, and biomarkers in the prediction of mortality and outcomes in
patients with end-stage kidney disease. Clin Cardiol. 2019 Jul; 42(7): 656-662.

3. Prognostic significance of renal dysfunction and its change pattern on outcomes in patients with acute
coronary syndrome treated with emergent percutaneous coronary intervention. Heart Vessels. 2019 May;
34(5):735-744.

4. Clinical significance of discrepant mid-wall late gadolinium enhancement in patients with nonischemic dilated
cardiomyopathy. Heart Vessels. 2018 May 26.

5. Associations of sensitive cardiac troponin-I with left ventricular morphology, function and prognosis in
end-stage renal disease patients with preserved ejection fraction. Heart Vessels. 2018 May 22.

6. Thrombus-Related Coronary High-Intensity Signal on T1-Weighted Magnetic Resonance Imaging Is a Potential
Predictor of Adverse Cardiovascular Events After Stent Implantation. JACC Cardiovasc Imaging.
2018　Sep;11(9):1364-1366.

7. Relationships Between Periventricular Epicardial Adipose Tissue Accumulation, Coronary Microcirculation, and
Left Ventricular Diastolic Dysfunction. Can J Cardiol. 2017 Nov; 33(11):1489-1497.

8. Association between duration of coronary occlusion and high-intensity signal on T1-weighted magnetic
resonance imaging among patients with angiographic total occlusion. Eur Radiol. 2017 Sep; 27(9) :3896-3903.

9. High-sensitive cardiac troponin T as a novel predictor for recurrence of atrial fibrillation after
radiofrequency catheter ablation. Europace. 2017 Dec 1;19(12):1951-1957.

10. The signal intensity of coronary culprit lesions on T1-weighted magnetic resonance imaging is directly
correlated with the accumulation of vulnerable morphologies. Int J Cardiol. 2017 Mar 15; 231:284-286.

11. Enhanced Vasa Vasorum Formation at Spasm Site　- Coincident Plexus or External Pathogenic Routes? Circ J.
2016 Sep 23; 80(10):2100-1.

12. The Clinical Value of High-Intensity Signals on the Coronary Atherosclerotic Plaques: Noncontrast
T1-Weighted Magnetic Resonance Imaging. Int J Mol Sci. 2016 Jul 21; 17(7). pii: E1187

13. Coronary plaque rupture with subsequent thrombosis typifies the culprit lesion of non-ST-segment-elevation
myocardial infarction, not unstable angina: non-ST-segment-elevation acute coronary syndrome study. Heart
Vessels. 2017 Mar; 32 (3):241-251.

14. Cholesterol crystal as a new feature of coronary vulnerable plaques: An optical coherence tomography study.
J Cardiol. 2017 Jan; 69(1):253-259. doi: 10.1016/j.jjcc.2016.04.003.

15. Pre-Procedural Serum Atrial Natriuretic Peptide Levels Predict Left Atrial Reverse Remodeling After Catheter
Ablation in Patients With Atrial Fibrillation. JACC Clin Electrophysiol. 2016 Apr; 2(2):151-158.

16. Successful treatment of very late drug-eluting stent thrombosis using bare-metal stent evaluated using
intravascular ultrasound and optical frequency domain imaging. Cardiovasc Interv Ther. 2017 Apr; 32(2):159-164.

17. New insights into spotty calcification and plaque rupture in acute coronary syndrome: an optical coherence
tomography study. Heart Vessels. 2016 Dec; 31(12):1915-1922.

18. Epicardial Adipose Tissue Accumulation Is Associated With Renal Dysfunction and Coronary Plaque Morphology
on Multidetector Computed Tomography. Circ J. 2016; 80(1):196-201.

19. Vascular Functional and Morphological Alterations in Smokers during Varenicline Therapy. Osaka City Med J.
2015 Jun; 61(1):19-30.

20. Clinical Characteristics of Late Gadolinium Enhancement in Patients with Cardiac Sarcoidosis. Osaka City Med
J. 2015 Jun; 61(1):9-17.

21. Localization of coronary high-intensity signals on T1-weighted magnetic resonance imaging: Relation to
plaque morphology and clinical severity of angina pectoris. JACC Cardiovasc Imaging. 2015

22. Detection of deep venous thrombosis using a pocket-size ultraspund. JACC Cardiovasc Imaging. 2015

23. Percutaneous carbon dioxide treatment using a gas mist generator enhances the collateral blood flow in the
ischemic hindlimb. J Atheroscler Thromb. 22(1): 38-51, 2015.

24. The utility of fully automated real-time three-dimensional echocardiography in the evaluation of left
ventricular diastolic function. J Cardiol. 66(1): 50-56, 2015.

25. Comparison of effects of sitagliptin and voglibose on left ventricular diastolic dysfunction in patients
with type 2 diabetes: results of the 3D trial. FESC, for Effect of a DPP-4 inhibitor on left ventricular
diastolic dysfunction in patients with type 2 diabetes and diabetic cardiomyopathy (3D) study investigators.
Cardiovasc Diabetol. 14:83, 2015.

26. Percutaneous carbon dioxide mist treatment has protective effects in experimental myocardial infarction. J
Pharmacol Sci. 127(4): 474-480, 2015.

27. Characteristic patterns of the longitudinal and circumferential distribution of calcium deposits by parent
coronary arteries observed from computed tomography angiography. Heart Vessels. Feb 25. [Epub ahead of print],
2015.

28. Repeated remote ischemic conditioning attenuates left ventricular remodeling via exosome-mediated
intercellular communication on chronic heart failure after myocardial infarction. Int J Cardiol. 178: 239-246,
2015.

29. Persistent epicardial adipose tissue accumulation is associated with coronary plaque vulnerability and
future acute coronary syndrome in non-obese subjects with coronary artery disease. Atherosclerosis. 237(1):
353-360. 2014.

30. DPP-4 inhibitor and alpha-glucosidase inhibitor equally improve endothelial function in patients with type 2
diabetes: EDGE study. Cardiovasc Diabetol. 13:110. 2014.

31. Serial assessment of arterial stiffness by cardio-ankle vascular index for prediction of future
cardiovascular events in patients with coronary artery disease. Hypertens Res. 37(11): 1014-1020, 2014.

32. Insulin resistance is associated with coronary plaque vulnerability: insight from optical coherence
tomography analysis. Eur Heart J Cardiovasc Imaging. 15(3): 284-291, 2014.

33. Diagnostic accuracy of transthoracic and transesophageal echocardiography for the diagnosis of bicuspid
aortic valve: comparison with operative findings. Osaka City Med J. 59(2): 69-78, 2013.

34. Prognosis of vulnerable plaque on computed tomographic coronary angiography with normal myocardial perfusion
image. Eur Heart J Cardiovasc Imaging. 15(3): 332-340, 2013.

35. The strain pattern, and not Sokolow-Lyon electrocardiographic voltage criteria, is independently associated
with anatomic left ventricular hypertrophy. Heart Vessels. 29(5): 638-644, 2013.

36. Serum n-3 to n-6 polyunsaturated fatty acids ratio correlates with coronary plaque vulnerability: an optical
coherence tomography study. Heart Vessels. 2013 Sep 5.

37. Tolvaptan attenuates left ventricular fibrosis after acute myocardial infarction in rats. J Pharmacol Sci.
2013 Sep 20;123 (1):58-66.

38. Prognostic value of coronary flow reserve on long-term cardiovascular outcomes in patients with chronic
kidney disease. Am J Cardiol. 2013 Oct 1;112 (7):928-32.

39. A case of a lesion containing an intracoronary thrombus detected as hyperintense plaque on T1-weighted
cardiovascular magnetic resonance in a patient with silent myocardial ischemia. J Cardiovasc Magn Reson. 2013
Jun 13;15: 50.

40. Very rapid effect of pitavastatin on microvascular function in comparison to rosuvastatin: reactive
hyperemia peripheral arterial tonometric study. Drug Des Devel Ther. 2013 May 3; 7:369-74.

41. Simultaneous assessment of endothelial function and morphology in the brachial artery using a new
semiautomatic ultrasound system. Hypertens Res. 2013 Aug;36(8):691-7.

42. Changes in serum cholesterol levels determine future risk of cardiovascular events in patients with acute
coronary syndrome in the Japanese Coronary Artery Disease (JCAD) Study. J Cardiol. 2013 Jun; 61(6):387-92.

43. Napkin-ring sign on coronary CT angiography for the prediction of acute coronary syndrome. JACC Cardiovasc
Imaging. 2013 Apr;6(4):448-57.

44. Impact of lesion length on functional significance in intermediate coronary lesions. Clin Cardiol. 2013 Mar;
36(3):172-7.

45. Effects of intravenous atrial natriuretic peptide and nitroglycerin on coronary vasodilation and flow
velocity determined using 3 T magnetic resonance imaging in patients with nonischemic heart failure. Heart
Vessels. 2013 Sep; 28(5):596-605.

46. Absence of coronary calcification with normal endothelial function. Circ J. 2012 Oct 25; 76(11):2544-5.

47. Adding thiazide to a rennin-angiotensin blocker regimen to improve left ventricular relaxation in diabetes
and nondiabetes patients with hypertension. Drug Des Devel Ther. 2012; 6:225-33.

48. Effects of intravenous atrial natriuretic peptide and nitroglycerin on coronary vasodilation and flow
velocity determined using 3 T magnetic resonance imaging in patients with nonischemic heart failure. Heart
Vessels. 2012 Sep 28.

49. Tolvaptan Improves Left Ventricular Dysfunction after Myocardial Infarction in Rats. Circ Heart Fail. 2012
Sep 14.

50. Peri-Atrial Epicardial Adipose Tissue Is Associated With New-Onset Nonvalvular Atrial Fibrillation. Circ J.
2012 Aug 22.

51. Direct measurement of multiple vena contracta areas for assessing the severity of mitral regurgitation using
3D TEE. JACC Cardiovasc Imaging. 2012 Jul; 5(7):669-76.

52. Preliminary observations of passive exercise using whole body periodic acceleration on coronary
microcirculation and glucose tolerance in patients with type 2 diabetes. J Cardiol. 2012 Oct; 60(4):283-7.

53. Impaired coronary flow reserve as a marker of microvascular dysfunction to predict long-term cardiovascular
outcomes, acute coronary syndrome and the development of heart failure. Circ J. 2012;76 (8):1958-64.

54. Prognostic value of aortic valve area index in asymptomatic patients with severe aortic stenosis. Am J
Cardiol. 2012 Jul 1;110 (1):93-7.

55. International Working Group for Intravascular Optical Coherence Tomography (IWG-IVOCT). Consensus standards
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